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Case Study

Transforming Clinical Data Intelligence and Operational Decision-Making with Aether for a Leading Academic Medical Center

A nonprofit academic medical center had clinical data spread across structured and unstructured sources, which slowed chart review and trial matching. Aether unified the data and added conversational queries, anomaly detection and AI recommendations.

Engagement at a glance
Client
Nonprofit academic medical center
Industry
Healthcare
Solution
ITHENA Aether AI Platform
Scope
Unified clinical data, NLP queries, anomaly detection, agentic AI
Headline result
30% less manual chart review
Opportunity for impact

Three numbers clinical teams moved.

Results after Aether unified the medical center's clinical and operational data.

30%

Reduction in manual chart review effort

Conversational queries replaced manual chart reviews when checking trial eligibility.

27%

Decrease in diagnostic errors

Predictive analytics flagged anomalies that helped clinicians avoid diagnostic errors.

25%

Improvement in trial matching speed

NLP matched patients to eligible clinical trials in less time.

About the client

Meet the organization and understand the context behind the transformation.

A nonprofit academic medical center delivering clinical care, research, and education across a network of hospitals and outpatient facilities. Partnering with ITHENA, the organization deployed Aether to consolidate structured and unstructured data, enabling NLP-driven conversational analytics and real-time anomaly detection. This AI-powered layer activated intelligent recommendations across workflows, resulting in faster diagnostics, improved trial-matching, and enhanced operational efficiency through immediate, actionable insights.

In their words
Our caregivers and researchers were working with an incredible depth of clinical data, but pulling it together fast enough to act on it was always the hard part. Aether changed that. Now the right information surfaces in seconds, not hours, and that has a real impact on both patient care and how we run the system.

— Chief Health Information Officer, Clinical Data Strategy
Key challenges faced

Deep data, slow answers.

Clinical data was rich but scattered, so pulling it together took hours.

  • Limited ability to unify structured and unstructured clinical data into a single accessible intelligence layer
  • Difficulty in efficiently connecting patients to relevant clinical trials, where eligibility has traditionally been limited
  • Delayed identification of operational and clinical anomalies across a multi-facility system
  • Limited capacity to convert vast volumes of data into timely, actionable insights
  • Lack of real-time, conversational access to clinical and operational data resulting in dependence on legacy dashboards and static reporting
Our solution

How ITHENA closed the gaps.

ITHENA's Aether platform empowered the client through:

Unified Data Integration

Consolidated structured and unstructured clinical data into a real-time, governed intelligence layer for system-wide visibility

NLP-Driven Insights

Enabled conversational queries to instantly match patients to eligible clinical trials, replacing manual chart reviews

Predictive Analytics and Anomaly Detection

Identified critical trends and anomalies to reduce errors and enhance diagnostic precision

Real-Time Visualization and Reporting

Shifted from static cycles to interactive visualizations to accelerate clinical and leadership decision-making

Agentic AI Recommendations

Delivered context-aware recommendations within workflows to improve care and operational confidence

Inside the console

Trial matches in minutes, not chart reviews.

An illustrative Aether view: manual review time falls as conversational queries match patients to eligible trials, with anomalies surfaced for clinicians.

aether.ithena.app/clinical/trial-matching
AAether ClinicalTrialsOperationsAsk Aether 3 OP
Trials/Eligibility screening/Last 12 weeks
Trial matching: screening time vs. patients matchedMatching getting faster
Wk 1Wk 6Wk 12
Manual review hoursPatients matchedAnomalies surfaced
Structured and unstructured records in one governed layer · 09:41:07
Since Aether went liveLive
30%Manual chart review, down
27%Diagnostic errors, down
25%Faster trial matching
48Active trials screened
Matches by trial area, share
Oncology34%
Cardiology22%
Neurology18%
Endocrinology14%
Other12%
Ask AetherAnswered
Which patients this week meet criteria for the heart failure trial?1m
23 candidates found; summary sent to the research coordinator1m
Lab value outside expected range flagged for review12m
Bed occupancy forecast refreshed for the weekend40m
Leadership dashboard updated with this morning’s data1h

Illustrative view. Unit names, counts, shares and activity are examples; the headline results are the client's.

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